proteasome inhibitor

proteasome inhibitor
ингибитор протеасом
лекарственное средство, блокирующее действием клеточных протеасом

English-Russian Biotechnology Glossary. . 2007.

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  • Proteasome inhibitor — Proteasome inhibitors are drugs that block the action of proteasomes, cellular complexes that break down proteins, like the p53 protein. Proteasome inhibitors are being studied in the treatment of cancer. In 2003, bortezomib was the first… …   Wikipedia

  • proteasome inhibitor — A drug that blocks the action of proteasomes. A proteasome is a large protein complex that helps destroy other cellular proteins when they are no longer needed. Proteasome inhibitors are being studied in the treatment of cancer …   English dictionary of cancer terms

  • Proteasome — Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm.cite journal |author=Peters JM, Franke WW, Kleinschmidt JA |title=Distinct 19 …   Wikipedia

  • Salinosporamide A — Chembox new ImageFile = Salinosporamide A.png ImageSize = IUPACName = OtherNames = (4R,5S) 4 (2 chloroethyl) 1 ((1S) cyclohex 2 enyl(hydroxy)methyl) 5 methyl 6 oxa 2 azabicyclo3.2.0heptane 3,7 dione Section1 = Chembox Identifiers CASNo = PubChem …   Wikipedia

  • Bortezomib — Drugbox IUPAC name = [(1 R ) 3 methyl 1 [(2 S ) 1 oxo 3 phenyl 2 [(pyrazinylcarbonyl)amino] propyl] amino] butyl] boronic acid CAS number = 179324 69 7 ATC prefix = L01 ATC suffix = XX32 PubChem = 93860 DrugBank = APRD00828 C=19 | H=25 | B=1 |… …   Wikipedia

  • Disulfiram — Systematic (IUPAC) name 1,1 ,1 ,1 [disulfanediylb …   Wikipedia

  • Peptidyl-glutamyl peptide-hydrolyzing activity — Peptidyl glutamyl peptide hydrolyzing (PGPH) enzyme activity is a means of proteolysis that cleaves peptide bonds in proteins immediately after acidic or branched chain amino acids. One of the three catalytic β subunits of the proteasome has PGPH …   Wikipedia

  • CDKN1B — Cyclin dependent kinase inhibitor 1B (p27, Kip1) PDB rendering based on 1jsu …   Wikipedia

  • Renal cell carcinoma — For other uses, see RCC (disambiguation). Main article: Kidney cancer Renal cell carcinoma Classification and external resources Micrograph of the most common t …   Wikipedia

  • EIF2A — Eukaryotic translation initiation factor 2A, 65kDa, also known as EIF2A, is a human gene. PBB Summary section title = summary text = EIF2A is a 65 kD protein that catalyzes the formation of puromycin sensitive 80S preinitiation complexes (Zoll et …   Wikipedia

  • Epigallocatechin gallate — EGCG redirects here. For the software, see Extended GCG. Epigallocatechin gallate IUPAC name …   Wikipedia


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